I keeping getting the error message from above on multiple computers that I administer. I wasn't sure if I should be posting this on SuperUser or ServerFault so my apologizes if it should go there...

Basically, I have at least 5 computers of varying ages (some fresh out of the box!) throwing the above error. X:\ is one of our network drives that is mapped for users. Most of the time if you shut down the biggest application it will fix the problem, but it's becoming an increasing issue, and I can't keep running around fixing it manually.

I have tried to do some research, but most of it just states the obvious without supplying a permanent fix.

The machines are all running Win XP SP3, with at least 2gb of ram.

Sorry for the delay in getting back to people... a lot of good questions.

To respond back to people...

1. It is a windows 2003 server that houses the file share.
2. We have about 175 users, however i cannot state how many are actually accessing the information at a single moment. Considering that this is our largest file share, I would say that probably at least 100+.
3. The files we work with are large, but not that big considering that we do a lot of graphical and video work. ~50mb. That being said, this is error occurs simply when trying to gain access to the server itself, not actual files.
4. When I say close a program, I mean that it can be any program. It doesn't matter which program. It varies from machine to machine, and from day to day. Some days it is Firefox, some days it is Outlook, some days it is Excel. There doesn't seem to be a common bond behind which application could be causing the problem.

Thank you for the articles, and the recommendation on paging files. I will have to look into that. None of our computers are set to hibernate, so I am going to rule that out.